Dental OSCE (Objective Structured Clinical Examination) Practice Exam

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Which analgesic is considered safe for a patient with kidney disease?

Aspirin
Ibuprofen
Tylenol (acetaminophen)
Naproxen

The correct answer is: Tylenol (acetaminophen)

Tylenol, known generically as acetaminophen, is considered safe for patients with kidney disease due to its metabolic pathway and lower potential for nephrotoxicity compared to nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen. Acetaminophen is primarily metabolized by the liver and does not significantly affect kidney function or exacerbate renal impairment when taken at recommended doses. In contrast, NSAIDs such as ibuprofen and naproxen can lead to decreased renal blood flow and glomerular filtration rate, potentially causing further harm to individuals with pre-existing kidney conditions. Aspirin, while sometimes used in certain clinical situations, also carries risks for those with impaired kidney function, particularly in high doses where it can lead to complications. Overall, acetaminophen is often the analgesic of choice for patients with kidney disease because it effectively manages pain without the adverse renal effects commonly associated with other analgesics, making it a safer alternative in this context.